Human Leukocyte Antigen (HLA) typing is a crucial genetic test used to determine the compatibility between organ and bone marrow donors and recipients. It helps identify specific proteins on the surface of white blood cells, which are essential for immune system function. Accurate HLA matching can significantly improve the success rates of transplants and reduce the risk of rejection.
If you are considering HLA typing, understanding the HLA typing test price in India and related factors is essential for making informed healthcare decisions.
What is HLA Typing?
HLA typing involves analyzing genes that code for HLA proteins. These proteins play a vital role in the immune system, helping the body distinguish between its own cells and foreign cells. There are several HLA genes, including HLA-A, HLA-B, HLA-C, HLA-DR, and HLA-DQ. Testing these markers allows doctors to find suitable donors for kidney, liver, bone marrow, and other transplants.
HLA typing is also used in:
- Bone marrow transplantation – for treating conditions like leukemia and aplastic anemia.
- Organ transplantation – to reduce graft rejection.
- Disease association studies – certain HLA types are linked to autoimmune disorders like Type 1 diabetes and rheumatoid arthritis.
Methods of HLA Typing
There are two primary techniques for HLA typing:
- Serological (antibody-based) method – This older method uses antibodies to detect HLA antigens on the surface of white blood cells. It is less precise but can provide rapid results in urgent cases.
- Molecular (DNA-based) method – This modern method analyzes DNA for HLA genes using PCR (Polymerase Chain Reaction) and sequencing techniques. It is more accurate and widely preferred for transplant compatibility testing.
Factors Affecting HLA Typing Test Price in India
The cost of HLA typing in India can vary depending on multiple factors:
- Type of test: DNA-based HLA typing is more expensive than serological methods due to advanced technology and higher accuracy.
- Number of loci tested: Testing for multiple HLA genes increases precision but also the cost.
- Laboratory reputation and technology: Reputed labs with state-of-the-art equipment may charge higher prices.
- Location: Prices can differ slightly across cities and regions.
HLA Typing Test Price in India – 2025
As of 2025, the HLA typing test price in India typically ranges from ₹6,000 to ₹20,000, depending on the factors mentioned above. DNA-based typing for all major loci (HLA-A, B, C, DR, DQ) generally falls on the higher end of the spectrum, while serological testing is more economical.
It is important to consult a certified genetic testing laboratory like Medgenome Labs, which offers accurate, reliable, and standardized HLA typing services. Medgenome’s advanced testing methods ensure precise donor-recipient matching, which is crucial for successful transplant outcomes.
Choosing the Right Lab
When selecting a lab for HLA typing, consider:
- Accreditation and certifications (ISO, NABL)
- Experience in transplant-related genetic testing
- Turnaround time for results
- Transparent pricing and counseling services
Conclusion
HLA typing is a vital step in ensuring successful organ and bone marrow transplants. With the updated HLA typing test price in India ranging between ₹6,000 and ₹20,000, patients and families can plan better for this essential procedure. Opting for a reliable lab like Medgenome Labs guarantees accurate results and expert guidance throughout the testing process.
Investing in precise HLA testing not only improves transplant success rates but also ensures better long-term health outcomes for recipients.
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