Fildena 100 pill is used to treat men's ED. It contains Sildenafil Citrate, which helps make the blood circulate smoothly in the male sex organs. It also helps in getting and maintaining an erection when sexual stimulation occurs.
It works by blocking the PDE-5 hormones that cause erectile dysfunction in males. It increases blood flow to the penis and helps achieve hard erections.
It is a prescription pill used to treat erectile dysfunction and pulmonary arterial hypertension in both men and women. It is one of only four phosphodiesterase type 5 (PDE5) inhibitors commercially available today.
It is an oral pill in two forms: an oral tablet and a liquid suspension. It is also available in an injection only given by a doctor.
In men with erectile dysfunction, sildenafil helps the arteries in the penis expand to allow more blood flow and firmer, longer-lasting erections. It also works by relaxing and widening the streets in the lungs to improve blood circulation during periods of exercise.
PDE5 inhibitors block enzymes that make it more difficult for blood vessels to dilate and circulate freely throughout your body. They work by blocking the action of PDE5, which is responsible for breaking down another substance called cyclic guanosine monophosphate.
This allows the arteries to relax and widen, lowering pulmonary blood pressure to the heart. This decreases the risk of a serious condition known as the vaso-occlusive crisis, which occurs in some people with pulmonary arterial hypertension.
It may take a few days to get the full effects when you start taking this medication. It isn't usually as effective after a high-fat meal, so don't eat a big meal before you take it.
Before you take this medication, tell your doctor if you have any of these conditions: diabetes, high or low blood pressure, kidney disease, liver disease, or a history of heart attack, stroke, or other problems with your heart rhythm. If you have any of these conditions, your doctor will adjust the dose or monitor you carefully for side effects.
Sildenafil is safe and effective when taken as prescribed by your doctor. It is not recommended for use in children under 18 and should not be used by pregnant or lactating women.
The most common side effect of sildenafil is a headache. However, it can also cause several other unwanted side effects. These side effects can be mild or severe. Some can be life-threatening. If you experience these side effects, call your doctor immediately.
Phosphodiesterase type 5 (PDE5) inhibitors are oral phosphodiesterase inhibitors that inhibit the breakdown of cyclic guanosine monophosphate (cGMP). The cGMP pathway plays an important role in regulating blood pressure by causing smooth muscle cells to relax, thereby increasing blood flow. The available PDE5 inhibitors differ in their affinity and selectivity for the cGMP isoform, determining their efficacy and safety profile.
Sildenafil, vardenafil, and tadalafil are competitive phosphodiesterase-5 inhibitors that block the degradation of cGMP. These agents can treat erectile dysfunction and pulmonary arterial hypertension by reducing pulmonary vascular pressure by promoting vasodilation.
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